Time ÷ duration of the refractory period
1 ÷ duration of the refractory period
Figure 1 shows the changes in the permeability of a section of an axon membrane to two ions that are involved in the production of an action potential. Use the information in Figure 1 to calculate the maximum frequency of action potentials per second along the axon. Show your working.
Step 1: Determine the duration of the refractory period
From the graph: 2.75 milliseconds
Step 2: Convert this to seconds
0.00275 seconds
Step 3: Insert relevant figures into the equation
Time ÷ duration of the refractory period
1 ÷ 0.00275 = 363.63
Answer = 364 action potentials sec-1
It is very important to check the units given in the question. For example, the duration of the refractory period may be given in milliseconds but the answer must be in action potentials sec-1. 1000 milliseconds = 1 seconds!
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