Skills: Analysing DNA Methylation Patterns Methylation of DNA Methyl groups (-CH3) can be directly added to DNA to change the activity of a gene DNA methylation commonly involves the direct additio...
Modification of RNA In all kingdoms of life, gene expression can be regulated after an mRNA transcript has been produced Post-transcriptional modification of mRNA Helps prevent degradation mRNA is ...
Nucleosomes Regulate Transcription Nucleosomes are the structural unit of DNA packaging in eukaryotes that facilitate supercoiling Within a nucleosome, DNA is wrapped around proteins called histone...
Environment & Gene Expression Environment and Gene Expression An organism’s internal or external environment can influence gene expression patterns The levels of regulatory proteins or transcri...
The Promoter Region The function of the promoter Only some DNA sequences code for the production of polypeptides, these are called coding sequences Non-coding sequences produce functional RNA molec...
Skills: Nucleosomes & Molecular Visualisation Software Molecular visualisation software can be used to help understand molecular structures Macromolecules like protein, DNA, RNA and complex car...
Skills: The Hershey & Chase Experiment Which Biomolecule is the Heritable Material? DNA was identified in 1869 but many scientists assumed that protein was the heritable material owing to the f...
DNA Sequencing Application: Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing DNA sequencing allows for the nucleotide base...
Non-coding Regions of DNA DNA molecules are very long but only certain regions code for the production of polypeptides These are called coding sequences In humans only 1.5% of the genome contains c...
